The TSLP Polyclonal Antibody (CAB13134) is a valuable tool for researchers studying thymic stromal lymphopoietin (TSLP), a cytokine that plays a key role in immune regulation and inflammation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.TSLP is known for its ability to promote allergic inflammation and drive immune responses, making it a promising target for studies in allergy, asthma, and autoimmune diseases.
The TSLP Polyclonal Antibody binds specifically to TSLP, allowing for accurate detection and analysis in a variety of cell types.By utilizing the TSLP Polyclonal Antibody, researchers can gain valuable insights into the role of TSLP in immune regulation and the development of inflammatory disorders. This antibody is a valuable tool for advancing research in immunology, allergy, and related fields.
Product Name:
TSLP Rabbit Polyclonal Antibody
SKU:
CAB13134
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP (NP_149024.1).
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
85480
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSLP Rabbit pAb (CAB13134) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
