The TSHZ3 Polyclonal Antibody (CAB18479) is a valuable tool for researchers studying the TSHZ3 protein, a transcription factor that plays a key role in embryonic development and tissue differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting.TSHZ3 is known to regulate gene expression and cellular differentiation processes, making it a crucial player in developmental biology and tissue-specific functions. Its dysregulation has been linked to various diseases, including craniofacial abnormalities and neurological disorders.
By targeting TSHZ3 with this antibody, researchers can investigate its function in different cell types and gain valuable insights into its role in disease pathology.With its specificity and reliability, the TSHZ3 Polyclonal Antibody is an essential tool for studies in developmental biology, neuroscience, and genetics. Its ability to detect and analyze TSHZ3 protein expression in various experimental settings makes it an invaluable resource for understanding the molecular mechanisms underlying embryonic development and disease progression.
Product Name:
TSHZ3 Rabbit Polyclonal Antibody
SKU:
CAB18479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 791-890 of human TSHZ3 (NP_065907.2).
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients.
Purification Method:
Affinity purification
Gene ID:
57616
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSHZ3 Rabbit pAb (CAB18479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
