TSHZ3 Rabbit Polyclonal Antibody (CAB18479)
- SKU:
- CAB18479
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TSHZ3 Rabbit Polyclonal Antibody |
SKU: | CAB18479 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 791-890 of human TSHZ3 (NP_065907.2). |
Sequence: | DLTK GKSD KGCS LGSV LLSP TSTA PATS SSTV TTAK TSAV VSFM SNSP LREN ALSD ISDM LKNL TESH TSKS STPS SISE KSDI DGAT LEEA EEST PAQK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TSH3; ZNF537; TSHZ3 |
Positive Sample: | U-87MG,HepG2 |
Cellular Localization: | nucleoplasm, nucleus, plasma membrane |
Calculated MW: | 119kDa |
Observed MW: | 119kDa |
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients.
Purification Method: | Affinity purification |
Gene ID: | 57616 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |