The TSHR Polyclonal Antibody (CAB6781) is a valuable tool for researchers studying thyroid stimulating hormone receptor (TSHR) in various biological processes. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TSHR protein, this antibody allows for accurate detection and analysis in a range of cell types, making it an ideal choice for immunology and endocrinology research.TSHR plays a crucial role in regulating thyroid function by interacting with thyroid stimulating hormone (TSH) to control thyroid hormone production.
Dysregulation of TSHR is associated with thyroid disorders such as hyperthyroidism and Graves' disease, making it a key target for investigating these conditions. Understanding the function and expression of TSHR is essential for developing targeted therapies and diagnostic tools for thyroid-related diseases.The TSHR Polyclonal Antibody (CAB6781) offers researchers a reliable tool for investigating the role of TSHR in physiological and pathological conditions, providing valuable insights into thyroid function and related disorders.
Product Name:
TSHR Rabbit Polyclonal Antibody
SKU:
CAB6781
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7253
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat kidney, using TSHR Rabbit pAb (CAB6781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
