TSG101/VPS23 Rabbit Polyclonal Antibody (CAB2216)
- SKU:
- CAB2216
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | TSG101/VPS23 Rabbit Polyclonal Antibody |
SKU: | CAB2216 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 291-390 of human TSG101/VPS23 (NP_006283.1). |
Sequence: | LKKK DEEL SSAL EKME NQSE NNDI DEVI IPTA PLYK QILN LYAE ENAI EDTI FYLG EALR RGVI DLDV FLKH VRLL SRKQ FQLR ALMQ KARK TAGL SDLY |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50-1:200 |
Synonyms: | TSG10; VPS23; TSG101/VPS23 |
Positive Sample: | SH-SY5Y,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Late endosome membrane, Membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Purification Method: | Affinity purification |
Gene ID: | 7251 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |