The TSFM Polyclonal Antibody (CAB16094) is a vital tool for research involving TSFM, a protein involved in mitochondrial translation. This antibody, produced in rabbits, offers high reactivity with human samples and has been validated for use in Western blotting and immunohistochemistry applications.TSFM is a key component in the translation machinery of mitochondria, playing a crucial role in protein synthesis within these energy-producing organelles. Dysregulation of TSFM has been associated with various mitochondrial disorders and diseases, making it a target of interest in research on metabolic disorders, neurodegenerative diseases, and cancer.
By specifically binding to TSFM, this polyclonal antibody facilitates the detection and analysis of TSFM levels in various cell types and tissues. Its utility in studying mitochondrial protein synthesis and function makes it an essential tool for researchers focused on understanding the molecular mechanisms underlying various pathologies and identifying potential therapeutic targets.
Product Name:
TSFM Rabbit Polyclonal Antibody
SKU:
CAB16094
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-346 of human TSFM (NP_001166167.1).
This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSFM Rabbit pAb (CAB16094) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
