The TSC22D3 Polyclonal Antibody is a valuable tool for researchers studying the TSC22D3 protein, also known as Glucocorticoid-Induced Leucine Zipper (GILZ). This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blotting and other immunological assays.TSC22D3 is a key player in various cellular processes, including immune response regulation, inflammation, and apoptosis. It is known to be induced by glucocorticoids and plays a crucial role in modulating immune and inflammatory signaling pathways.
By targeting TSC22D3, researchers can gain insight into its functions and potentially develop targeted therapies for conditions such as inflammatory diseases, autoimmune disorders, and cancer.This antibody enables the detection and analysis of TSC22D3 protein in various cell types, providing researchers with a valuable tool for investigating its role in different physiological and pathological contexts. With its versatility and reliability, the TSC22D3 Polyclonal Antibody is a valuable asset for studies in immunology, cancer research, and beyond.
Product Name:
TSC22D3 Polyclonal Antibody
SKU:
CAB24661
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TSC22D3 (NP_004080.2).
This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1831
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of PC-12 cells using TSC22D3 Rabbit pAb (CAB24661) at dilution of 1:50 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
