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TSC22D3 Rabbit Polyclonal Antibody (CAB6779)

SKU:
CAB6779
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-TSC22D3 Antibody CAB6779
  • Cell Biology Antibodies 10 Anti-TSC22D3 Antibody CAB6779
  • Cell Biology Antibodies 10 Anti-TSC22D3 Antibody CAB6779
  • Cell Biology Antibodies 10 Anti-TSC22D3 Antibody CAB6779
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TSC22D3 Rabbit Polyclonal Antibody
SKU:CAB6779
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 58-134 of human TSC22D3 (NP_004080.2).
Sequence:MDLV KNHL MYAV REEV EILK EQIR ELVE KNSQ LERE NTLL KTLA SPEQ LEKF QSCL SPEE PAPE SPQV PEAP GGSA V
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:DIP; GILZ; DSIPI; TSC-22R; TSC22D3
Positive Sample:293T,Mouse spleen
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:15kDa
Observed MW:15kDa

This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:1831
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using TSC22D3 Rabbit pAb (CAB6779) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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