The TSC22D3 Polyclonal Antibody (CAB6779) is a valuable tool for researchers studying TSC22D3, a transcription factor known for its role in immune and inflammatory processes. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TSC22D3 protein, this antibody allows for the detection and analysis of TSC22D3 levels in various cell types, making it ideal for studies in immunology, inflammation, and cancer research.TSC22D3, also known as glucocorticoid-induced leucine zipper protein, is a key regulator of immune response and has been implicated in the pathogenesis of inflammatory diseases and cancer.
By understanding the molecular mechanisms and signaling pathways involving TSC22D3, researchers can gain insights into potential therapeutic targets for diseases such as autoimmune disorders, chronic inflammation, and cancer. The TSC22D3 Polyclonal Antibody is a crucial tool for investigating the role of TSC22D3 in these contexts and advancing research in the field.
Product Name:
TSC22D3 Rabbit Polyclonal Antibody
SKU:
CAB6779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 58-134 of human TSC22D3 (NP_004080.2).
Sequence:
MDLV KNHL MYAV REEV EILK EQIR ELVE KNSQ LERE NTLL KTLA SPEQ LEKF QSCL SPEE PAPE SPQV PEAP GGSA V
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
DIP; GILZ; DSIPI; TSC-22R; TSC22D3
Positive Sample:
293T,Mouse spleen
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
15kDa
Observed MW:
15kDa
This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1831
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using TSC22D3 Rabbit pAb (CAB6779) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
