TSC2 Rabbit Polyclonal Antibody (CAB16007)
- SKU:
- CAB16007
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TSC2 Rabbit Polyclonal Antibody |
SKU: | CAB16007 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1531-1807 of TSC2 (NP_000539.2). |
Sequence: | VQLL DQIP SYDT HKIA VLYV GEGQ SNSE LAIL SNEH GSYR YTEF LTGL GRLI ELKD CQPD KVYL GGLD VCGE DGQF TYCW HDDI MQAV FHIA TLMP TKDV DKHR CDKK RHLG NDFV SIVY NDSG EDFK LGTI KGQF NFVH VIVT PLDY ECNL VSLQ CRKD MEGL VDTS VAKI VSDR NLPF VARQ MALH ANMA SQVH HSRS NPTD IYPS KWIA RLRH IKRL RQRI CEEA AYSN PSLP LVHP PSHS KAPA QTPA EPTP GYEV GQRK RLIS SVED FTEF V |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:100 |
Synonyms: | LAM; TSC4; PPP1R160; TSC2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Peripheral membrane protein. |
Calculated MW: | 201kDa |
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
Purification Method: | Affinity purification |
Gene ID: | 7249 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |