The Tryptophanyl-tRNA Synthetase 1 Monoclonal Antibody is a cutting-edge tool for researchers studying protein biosynthesis and genetic regulation. This antibody, developed specifically for human samples, is highly specific and sensitive, allowing for precise detection of the Tryptophanyl-tRNA Synthetase 1 protein in various biological samples.Tryptophanyl-tRNA Synthetase 1 is a key enzyme involved in the process of protein translation, specifically in the attachment of tryptophan to its corresponding tRNA molecule. Dysregulation of this enzyme has been linked to various diseases, including cancer and neurodegenerative disorders, making it a valuable target for research in these areas.
With its high reactivity and specificity, this monoclonal antibody is ideal for use in applications such as Western blotting, immunofluorescence, and immunoprecipitation. By enabling the precise detection and analysis of Tryptophanyl-tRNA Synthetase 1, researchers can gain valuable insights into the molecular mechanisms underlying diseases and potentially uncover new therapeutic targets.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7453
Clone Number:
ARC2687
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human placenta using Tryptophanyl-tRNA synthetase 1 Rabbit mAb (CAB22440) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
