trxA Antibody (PACO33952)
- SKU:
- PACO33952
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
trxA Antibody (PACO33952)
The TRXA Antibody (PAC033952) is a polyclonal antibody designed for research involving TRXA, a key protein involved in redox regulation and antioxidant defense mechanisms. This antibody is raised in rabbits and has high reactivity with human samples, making it a valuable tool for studying oxidative stress and redox signaling pathways.TRXA, also known as thioredoxin, plays a crucial role in maintaining cellular redox balance by reducing disulfide bonds in target proteins. Its involvement in various cellular processes, including DNA synthesis, signal transduction, and apoptosis, underscores its importance in cell survival and response to oxidative stress.
The TRXA Antibody enables the detection and analysis of TRXA expression in different cell types, making it a versatile tool for research in areas such as cancer biology, neurodegenerative diseases, and aging.By studying the activity and regulation of TRXA, researchers can gain insights into the mechanisms underlying redox signaling and its impact on cellular function. This antibody is validated for use in Western blot applications, offering reliable results for investigating the role of TRXA in health and disease.
| Antibody Name: | trxA Antibody (PACO33952) |
| Antibody SKU: | PACO33952 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Thioredoxin-1 protein (2-109AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: trxA antibody at 2µg/ml + DH5alpha whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 12 kDa Observed band size: 12 kDa . |
| Background: | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. |
| Synonyms: | Thioredoxin 1 (Trx-1), trxA, fipA tsnC |
| UniProt Protein Function: | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P0AA25 |
| NCBI GenInfo Identifier: | 67005950 |
| NCBI Gene ID: | 23335415 |
| NCBI Accession: | NP_418228.2 |
| UniProt Secondary Accession: | P0AA25,P00274, P76750, Q2M889, Q47674, Q8XAT2 |
| UniProt Related Accession: | P0AA25 |
| Molecular Weight: | |
| NCBI Full Name: | thioredoxin 1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | trxAÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | thioredoxin |
| UniProt Protein Name: | Thioredoxin-1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Thioredoxin |
| UniProt Gene Name: | trxAÂ Â |
| UniProt Entry Name: | THIO_ECOLI |
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