The TRPV2 Polyclonal Antibody (CAB12367) is a valuable tool for researchers studying the TRPV2 protein, a member of the transient receptor potential vanilloid (TRPV) family involved in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By binding specifically to TRPV2, researchers can detect and analyze the protein in different cell types, making it an excellent choice for studies in neuroscience and pain research.TRPV2 is known to play a role in sensory perception, particularly in the detection of temperature and mechanical stimuli. Its involvement in processes such as nociception and cell migration highlights its importance in understanding pain pathways and potential therapeutic targets for pain management.
Research on TRPV2 is also relevant in the study of neurodegenerative diseases, as dysregulation of TRPV2 has been implicated in conditions such as neuropathic pain and migraine.By utilizing the TRPV2 Polyclonal Antibody, researchers can gain valuable insights into the functions and mechanisms of TRPV2, advancing our knowledge of sensory physiology and potential strategies for treating pain-related disorders. Investigating the role of TRPV2 may lead to the development of new therapies targeting this protein for pain relief and improved quality of life for patients suffering from chronic pain conditions.
Product Name:
TRPV2 Rabbit Polyclonal Antibody
SKU:
CAB12367
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 655-764 of human TRPV2 (NP_057197.2).
This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.
Purification Method:
Affinity purification
Gene ID:
51393
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRPV2 Rabbit pAb (CAB12367) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
