The TRPV1 Polyclonal Antibody (CAB8564) is a specialized research tool designed for investigating the Transient Receptor Potential Vanilloid 1 (TRPV1) protein, which plays a crucial role in pain sensation and inflammation. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an excellent choice for Western blot applications.TRPV1 is a key receptor involved in the detection of heat and pain, making it a promising target for the development of pain-relieving medications. By targeting TRPV1, researchers can gain insights into pain mechanisms and potentially discover new therapeutic strategies for pain management and inflammatory conditions.
The TRPV1 Polyclonal Antibody enables precise detection and analysis of TRPV1 protein levels in various cell types, offering valuable insights into its function and regulation. This antibody is an essential tool for studies in the fields of neuroscience, pain research, and drug discovery, providing researchers with the means to deepen their understanding of TRPV1 biology and its implications for human health.
Product Name:
TRPV1 Rabbit Polyclonal Antibody
SKU:
CAB8564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 725-839 of human TRPV1 (NP_061197.4).
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
7442
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using TRPV1 Rabbit pAb (CAB8564) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
