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TRPV1 Monoclonal Antibody

SKU:
CAB23386
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

TRPV1 Monoclonal Antibody (CAB23386)

The TRPV1 Monoclonal Antibody is a powerful tool for researchers studying the TRPV1 protein, a key player in sensory neuron function and pain perception. This antibody, produced through a monoclonal antibody technique, offers high specificity and sensitivity in detecting TRPV1 in various experimental samples.TRPV1, also known as the capsaicin receptor, plays a crucial role in mediating sensations of heat, pain, and inflammation. By targeting TRPV1 with this monoclonal antibody, researchers can gain insights into the function of this protein in various physiological and pathological processes.

Whether investigating pain mechanisms, studying the role of TRPV1 in inflammatory conditions, or exploring potential therapeutic interventions targeting TRPV1, this monoclonal antibody is a valuable tool for researchers in the fields of neuroscience, pharmacology, and pain research. Its reliability and specificity make it an essential component in any study involving TRPV1.

Product Name:TRPV1 Monoclonal Antibody
Product Code:CAB23386
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57842
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse brain, Rat brain
Cellular Location:Cell junction, Cell membrane, Cell projection, dendritic spine membrane, postsynaptic cell membrane, synaps

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 725-839 of human TRPV1 (NP_542435.2).
Sequence:KLLQV GYTPD GKDDY RWCFR VDEVN WTTWN TNVGI INEDP GNCEG VKRTL SFSLR SSRVS GRHWK NFALV PLLRE ASARD RQSAQ PEEVY LRQFS GSLKP EDAEV FKSPA ASGEK
Synonyms:VR1
Calculated MW:95kDa
Observed MW:100kDa

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