TRPM7 Rabbit Polyclonal Antibody (CAB10075)
- SKU:
- CAB10075
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRPM7 Rabbit Polyclonal Antibody |
SKU: | CAB10075 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 756-855 of human TRPM7 (NP_060142.3). |
Sequence: | NSWY KVIL SILV PPAI LLLE YKTK AEMS HIPQ SQDA HQMT MDDS ENNF QNIT EEIP MEVF KEVR ILDS NEGK NEME IQMK SKKL PITR KFYA FYHA PIVK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK; TRPM7 |
Positive Sample: | Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 213kDa |
Observed MW: | 230kDa |
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function.
Purification Method: | Affinity purification |
Gene ID: | 54822 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |