The TRPM4 Polyclonal Antibody (CAB10146) is a key tool for researchers studying TRPM4, a member of the transient receptor potential (TRP) ion channel family that plays a crucial role in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TRPM4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in neuroscience, cardiovascular research, and ion channel biology.
TRPM4 is known for its involvement in regulating cell membrane potential and calcium signaling, making it a potential therapeutic target for a range of conditions including cardiac arrhythmias, neurological disorders, and hypertension. By further understanding the function of TRPM4, researchers may uncover novel insights into disease mechanisms and potential treatment strategies. The TRPM4 Polyclonal Antibody is a valuable tool for unraveling the complexities of this important ion channel and advancing scientific knowledge in these critical research areas.
Product Name:
TRPM4 Rabbit Polyclonal Antibody
SKU:
CAB10146
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRPM4 (NP_060106.2).
The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium.
Purification Method:
Affinity purification
Gene ID:
54795
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat brain, using TRPM4 antibody (CAB10146) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
