TRPM2 Rabbit Polyclonal Antibody (CAB6137)
- SKU:
- CAB6137
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRPM2 Rabbit Polyclonal Antibody |
SKU: | CAB6137 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1204-1503 of human TRPM2 (NP_003298.1). |
Sequence: | SSEA DVPT LASQ KAAE EPDA EPGG RKKT EEPG DSYH VNAR HLLY PNCP VTRF PVPN EKVP WETE FLIY DPPF YTAE RKDA AAMD PMGD TLEP LSTI QYNV VDGL RDRR SFHG PYTV QAGL PLNP MGRT GLRG RGSL SCFG PNHT LYPM VTRW RRNE DGAI CRKS IKKM LEVL VVKL PLSE HWAL PGGS REPG EMLP RKLK RILR QEHW PSFE NLLK CGME VYKG YMDD PRNT DNAW IETV AVSV HFQD QNDV ELNR LNSN LHAC DSGA SIRW QVVD RRIP LYAN HKTL LQKA AAEF GAHY |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:100 |
Synonyms: | KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1; TRPM2 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 171kDa |
Observed MW: | 171kDa |
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.
Purification Method: | Affinity purification |
Gene ID: | 7226 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |