TRPM1 Rabbit Polyclonal Antibody (CAB17509)
- SKU:
- CAB17509
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRPM1 Rabbit Polyclonal Antibody |
SKU: | CAB17509 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1460-1540 of human TRPM1 (NP_002411.3). |
Sequence: | SITD QQLT TEWQ CQVQ KITR SHST DIPY IVSE AAVQ AEHK EQFA DMQD EHHV AEAI PRIP RLSL TITD RNGM ENLL SVKP D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MLSN1; CSNB1C; LTRPC1; TRPM1 |
Positive Sample: | SK-MEL-28 |
Conjugate: | Unconjugated |
Cellular Localization: | axon, plasma membrane |
Calculated MW: | 182kDa |
Observed MW: | 182kDa |
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4308 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |