TRPC6 Rabbit Polyclonal Antibody (CAB8155)
- SKU:
- CAB8155
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRPC6 Rabbit Polyclonal Antibody |
SKU: | CAB8155 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 466-565 of human TRPC6 (NP_004612.2). |
Sequence: | EGTK LLPN ETST DNAK QLFR MKTS CFSW MEML IISW VIGM IWAE CKEI WTQG PKEY LFEL WNML DFGM LAIF AASF IARF MAFW HASK AQSI IDAN DTLK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | TRP6; FSGS2; TRPC6 |
Positive Sample: | Mouse pancreas,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 106kDa |
Observed MW: | 106kDa |
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Purification Method: | Affinity purification |
Gene ID: | 7225 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |