TRPC6 Rabbit Polyclonal Antibody (CAB15107)
- SKU:
- CAB15107
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRPC6 Rabbit Polyclonal Antibody |
SKU: | CAB15107 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 732-931 of human TRPC6 (NP_004612.2). |
Sequence: | QEIE DDAD VEWK FARA KLWF SYFE EGRT LPVP FNLV PSPK SLFY LLLK LKKW ISEL FQGH KKGF QEDA EMNK INEE KKLG ILGS HEDL SKLS LDKK QVGH NKQP SIRS SEDF HLNS FNNP PRQY QKIM KRLI KRYV LQAQ IDKE SDEV NEGE LKEI KQDI SSLR YELL EEKS QNTE DLAE LIRE LGEK LSME PNQE ETNR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | TRP6; FSGS2; TRPC6 |
Positive Sample: | SGC996,Mouse lung,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 106kDa |
Observed MW: | 110kDa |
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Purification Method: | Affinity purification |
Gene ID: | 7225 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |