The TRPC3 Polyclonal Antibody (CAB7742) is a valuable tool for researchers studying TRPC3, a member of the transient receptor potential (TRP) superfamily involved in various cellular functions such as calcium signaling and ion transport. This antibody, produced in rabbits, is highly specific and reacts strongly with human samples, making it ideal for Western blot applications. It binds specifically to the TRPC3 protein, enabling precise detection and analysis in a wide range of cell types.TRPC3 plays a crucial role in intracellular calcium signaling, which is essential for processes like cell proliferation, differentiation, and apoptosis.
Dysregulation of TRPC3 has been implicated in various diseases including cardiac hypertrophy, neurological disorders, and certain types of cancer. By understanding the function of TRPC3, researchers can uncover potential therapeutic targets for these conditions, ultimately leading to the development of new treatment strategies.Overall, the TRPC3 Polyclonal Antibody is a valuable tool for investigating the role of TRPC3 in cellular signaling pathways, providing essential insights for advancing our understanding of disease mechanisms and potentially identifying new therapeutic approaches.
Product Name:
TRPC3 Rabbit Polyclonal Antibody
SKU:
CAB7742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TRPC3 (NP_001124170.1).
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7222
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRPC3 antibody (CAB7742) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
