The TRPC1 Rabbit Monoclonal Antibody (CAB4016) is specifically designed for research involving TRPC1, a member of the transient receptor potential canonical (TRPC) family of cation channels. This antibody, produced using rabbit monoclonal technology, is highly reactive with human samples and is validated for use in a variety of applications, including Western blot and immunohistochemistry.TRPC1 plays a crucial role in various physiological processes, including calcium signaling, cell proliferation, and migration. Dysregulation of TRPC1 has been implicated in several diseases, such as neurological disorders, cardiovascular diseases, and cancer.
Therefore, studying the expression and function of TRPC1 using this antibody can provide valuable insights into the underlying mechanisms of these conditions.With its high specificity and sensitivity, the TRPC1 Rabbit Monoclonal Antibody (CAB4016) enables precise detection and analysis of TRPC1 protein in various cell types and tissues. This makes it an ideal tool for researchers working in the fields of neuroscience, cardiology, and oncology, who are interested in unraveling the role of TRPC1 in health and disease.
Product Name:
TRPC1 Rabbit Monoclonal Antibody
SKU:
CAB4016
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (P48995).
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7220
Clone Number:
ARC0884
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRPC1 Rabbit mAb (CAB4016) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
