The TROVE2 Polyclonal Antibody (CAB6986) is a valuable tool for researchers studying the TROVE2 protein, a key factor in RNA metabolism and processing. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TROVE2 protein, this antibody allows for precise detection and analysis in various cell types, making it an essential tool for investigations in molecular biology and RNA research.TROVE2, also known as Ro 60 kDa, plays a crucial role in the efficient functioning of the Ro RNP complex involved in RNA stabilization and processing.
Dysregulation of TROVE2 has been implicated in various diseases, including autoimmune disorders and cancer, highlighting the importance of understanding its biological functions. Consequently, research using the TROVE2 Polyclonal Antibody can provide valuable insights into the mechanisms underlying these conditions and may contribute to the development of targeted therapies in the future.
Product Name:
TROVE2 Rabbit Polyclonal Antibody
SKU:
CAB6986
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TROVE2 (NP_004591.2).
Enables RNA binding activity. Involved in cellular response to interferon-alpha and regulation of gene expression. Located in cytosol and nucleoplasm. Part of ribonucleoprotein complex.
Purification Method:
Affinity purification
Gene ID:
6738
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TROVE2 antibody (CAB6986) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
