The Tropomodulin-1 Polyclonal Antibody (CAB4160) is a powerful tool for researchers studying Tropomodulin-1, a key regulator of actin assembly and cytoskeletal organization in cells. This antibody, developed using rabbits as the host, exhibits high specificity and reactivity with human samples, making it a reliable tool for Western blot applications. By specifically targeting the Tropomodulin-1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology, cytoskeleton dynamics, and cancer research.Tropomodulin-1 is a critical player in maintaining the structure and function of the actin cytoskeleton, which is essential for various cellular processes such as cell shape maintenance, cell motility, and intracellular transport.
Dysregulation of Tropomodulin-1 has been linked to several diseases, including cancer metastasis and neurodegenerative disorders. Therefore, investigating the role of Tropomodulin-1 using this antibody could provide valuable insights into cellular function and disease mechanisms, paving the way for potential therapeutic interventions targeting the actin cytoskeleton.
Product Name:
TMOD1 Rabbit Polyclonal Antibody
SKU:
CAB4160
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human TMOD1 (NP_003266.1).
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7111
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TMOD1 antibody (CAB4160) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
