The TRMT6/61B Polyclonal Antibody (CAB8067) is a valuable tool for researchers studying TRMT6/61B, a protein complex involved in tRNA modifications. This antibody, produced using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the TRMT6/61B protein complex, this antibody allows for precise detection and analysis in a variety of cell types, making it well-suited for investigations in molecular biology and RNA biology.TRMT6/61B is known for its role in catalyzing the methylation of tRNAs, a process crucial for proper tRNA function and protein synthesis.
Dysfunction of this protein complex has been linked to various diseases, including cancer and neurological disorders, highlighting the importance of studying its mechanisms and functions. The TRMT6/61B Polyclonal Antibody provides researchers with a reliable tool for exploring the biological functions and potential therapeutic targets associated with TRMT6/61B.
Product Name:
TRMT61B Rabbit Polyclonal Antibody
SKU:
CAB8067
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT61B (NP_060380.3).
Enables mRNA (adenine-N1-)-methyltransferase activity; rRNA (adenine) methyltransferase activity; and tRNA (adenine-N1-)-methyltransferase activity. Involved in mRNA methylation; mitochondrial tRNA methylation; and protein homooligomerization. Located in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
55006
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TRMT61B antibody (CAB8067) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
