The TRMT6 Polyclonal Antibody (CAB9212) is a high-quality antibody produced for research purposes involving TRMT6, a protein involved in tRNA methylation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to TRMT6, this antibody enables accurate detection and analysis of the protein in various cell types, making it an excellent tool for studies in molecular biology and RNA processing.TRMT6 is an essential enzyme in the tRNA methylation pathway, playing a crucial role in maintaining the fidelity of protein translation. Dysregulation of TRMT6 has been implicated in various diseases, including cancer and neurological disorders, making it a promising target for therapeutic interventions.
By studying the function of TRMT6, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop novel treatment strategies.Overall, the TRMT6 Polyclonal Antibody (CAB9212) is a valuable tool for researchers interested in exploring the role of TRMT6 in cellular processes and disease pathology. Its high specificity and reliability make it a trusted reagent for experiments aiming to uncover the functions of this important protein in health and disease.
Product Name:
TRMT6 Rabbit Polyclonal Antibody
SKU:
CAB9212
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TRMT6 (NP_057023.2).
This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51605
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRMT6 Rabbit pAb (CAB9212) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.