The TRMT2B Polyclonal Antibody (CAB3509) is a vital tool for researchers studying TRMT2B, a protein involved in tRNA methylation and RNA modification. This antibody, produced in rabbits, has high specificity and sensitivity for detecting TRMT2B in human samples, making it suitable for use in Western blot applications. By targeting the TRMT2B protein, this antibody allows for the precise detection and analysis of TRMT2B expression in a variety of cell types, making it ideal for investigations in molecular biology and RNA processing.
TRMT2B is essential for tRNA methylation, a crucial process in protein synthesis and gene expression regulation. Dysregulation of TRMT2B has been linked to various diseases, including cancer and neurodevelopmental disorders. By studying TRMT2B function and expression levels, researchers can gain insights into its role in disease progression and potentially identify new therapeutic targets. The TRMT2B Polyclonal Antibody provides a valuable tool for advancing research in the fields of molecular biology and RNA biology.
Product Name:
TRMT2B Rabbit Polyclonal Antibody
SKU:
CAB3509
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2).
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
79979
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRMT2B antibody (CAB3509) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
