The TRMT2A Polyclonal Antibody (CAB5975) is a valuable tool for research involving TRMT2A, a protein involved in RNA modification and epigenetic regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for various applications in molecular biology and biochemistry research.TRMT2A plays a key role in tRNA modification, particularly in the methylation of tRNAs to ensure proper translation of genetic information. Dysregulation of TRMT2A has been implicated in several diseases, including cancer and neurological disorders. Understanding the function and regulation of TRMT2A is important for uncovering its role in disease development and progression.
The TRMT2A Polyclonal Antibody binds specifically to the TRMT2A protein, allowing for accurate detection and analysis in cell lysates and tissue samples. Its high sensitivity and specificity make it an ideal tool for studying TRMT2A expression levels, interactions, and localization in various cell types and experimental conditions. Researchers in the fields of molecular biology, biochemistry, and genetics will find this antibody invaluable for their studies on RNA modification and epigenetic regulation.
Product Name:
TRMT2A Rabbit Polyclonal Antibody
SKU:
CAB5975
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human TRMT2A/HTF9C (NP_073564.3).
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRMT2A/HTF9C Rabbit pAb (CAB5975) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
