The TRMT112 Polyclonal Antibody (CAB14310) is a valuable tool for researchers studying TRMT112, a protein involved in tRNA methylation and gene expression regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically targets the TRMT112 protein, allowing for detection and analysis in various cell types, making it an excellent choice for studies in genetics and molecular biology.TRMT112 is a key player in the process of tRNA methylation, essential for maintaining proper protein synthesis and cellular function.
Dysregulation of tRNA modifications has been linked to various diseases including cancer and neurological disorders. Research into TRMT112 can provide insights into the mechanisms underlying these conditions and potentially lead to the development of novel therapeutic strategies targeting tRNA modifications.By utilizing the TRMT112 Polyclonal Antibody, researchers can delve deeper into the role of TRMT112 in cellular processes and disease pathogenesis, advancing our understanding of tRNA biology and its implications for human health.
Product Name:
TRMT112 Rabbit Polyclonal Antibody
SKU:
CAB14310
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human TRMT112 (NP_057488.1).
cytosol, nucleoplasm, perinuclear region of cytoplasm
Calculated MW:
14kDa
Observed MW:
14kDa
Enables protein heterodimerization activity and protein methyltransferase activity. Involved in macromolecule methylation and positive regulation of rRNA processing. Located in nucleoplasm and perinuclear region of cytoplasm. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
51504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRMT112 Rabbit pAb (CAB14310) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
