TRMT1 Rabbit Polyclonal Antibody (CAB7116)
- SKU:
- CAB7116
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | TRMT1 Rabbit Polyclonal Antibody |
SKU: | CAB7116 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-659 of human TRMT1 (NP_060192.1). |
Sequence: | PSLL QLRS ALLH ADFR VSLS HACK NAVK TDAP ASAL WDIM RCWE KECP VKRE RLSE TSPA FRIL SVEP RLQA NFTI REDA NPSS RQRG LKRF QANP EANW GPRP RARP GGKA ADEA MEER RRLL QNKR KEPP EDVA QRAA RLKT FPCK RFKE GTCQ RGDQ CCYS HSPP TPRV SADA APDC PETS NQTP PGPG AAAG PGID |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TRM1; MRT68; TRMT1 |
Positive Sample: | MCF7,HL-60,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 72kDa |
Observed MW: | 90kDa |
This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.
Purification Method: | Affinity purification |
Gene ID: | 55621 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |