TRIP6 Antibody (PACO17321)
- SKU:
- PACO17321
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TRIP6 Antibody (PACO17321)
The TRIP6 Antibody (PAC017321) is a high-quality polyclonal antibody designed for research involving TRIP6, a protein known for its role in cell adhesion and signaling processes. This antibody, generated in rabbits, is highly specific to TRIP6 and is validated for use in various applications, including Western blot and immunofluorescence.TRIP6, also known as Thyroid Hormone Receptor Interactor 6, has been implicated in cell migration, proliferation, and differentiation, making it a critical player in various cellular processes. By targeting TRIP6 with this antibody, researchers can investigate its function in different cell types and explore its potential role in diseases such as cancer, cardiovascular disorders, and neuronal development.
With its high reactivity and specificity, the TRIP6 Antibody (PAC017321) is a valuable tool for studies in molecular biology, cell biology, and disease research. It enables researchers to detect and analyze TRIP6 protein expression, paving the way for a deeper understanding of its function and potential therapeutic applications.
| Antibody Name: | TRIP6 Antibody (PACO17321) |
| Antibody SKU: | PACO17321 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human TRIP6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17321(TRIP6 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid, (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Synonyms: | thyroid hormone receptor interactor 6 |
| UniProt Protein Function: | TRIP6: thyroid receptor interacting protein 6 specifically interacts with the ligand-binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction. Interacts with PTPN13. Functions downstream of the activated LPA(2) receptor and is involved in cell adhesion and migration.Protein type: Nuclear receptor co-regulator; Motility/polarity/chemotaxis; Adaptor/scaffoldChromosomal Location of Human Ortholog: 7q22Cellular Component: interleukin-1 receptor complex; cytoskeleton; focal adhesion; cytoplasm; plasma membrane; nucleusMolecular Function: protein binding; interleukin-1 receptor binding; zinc ion binding; thyroid hormone receptor binding; kinase bindingBiological Process: release of cytoplasmic sequestered NF-kappaB; focal adhesion formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of cell migration |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15654 |
| NCBI GenInfo Identifier: | 20981729 |
| NCBI Gene ID: | 7205 |
| NCBI Accession: | Q15654.3 |
| UniProt Secondary Accession: | Q15654,O15170, O15275, Q9BTB2, Q9BUE5, Q9BXP3, Q9UNT4 A4D2E7, F2ZC07, F2ZC08 |
| UniProt Related Accession: | Q15654 |
| Molecular Weight: | 476 |
| NCBI Full Name: | Thyroid receptor-interacting protein 6 |
| NCBI Synonym Full Names: | thyroid hormone receptor interactor 6 |
| NCBI Official Symbol: | TRIP6Â Â |
| NCBI Official Synonym Symbols: | OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2Â Â |
| NCBI Protein Information: | thyroid receptor-interacting protein 6; zyxin related protein 1; TR-interacting protein 6; OPA-interacting protein 1; thyroid hormone receptor interacting protein 6 |
| UniProt Protein Name: | Thyroid receptor-interacting protein 6 |
| UniProt Synonym Protein Names: | Opa-interacting protein 1; OIP-1; Zyxin-related protein 1; ZRP-1 |
| Protein Family: | Thyroid receptor-interacting protein |
| UniProt Gene Name: | TRIP6Â Â |
| UniProt Entry Name: | TRIP6_HUMAN |
| Antibodies |
| TRIP6 Antibody (PACO12929) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
TRIP6 Antibody (PACO12929)
$551
TRIP6 Antibody (PACO17320)
$407
Human Thyroid Hormone Receptor Interactor 6 (TRIP6) ELISA Kit (HUDL02992)
$779
Mouse Thyroid Hormone Receptor Interactor 6 (TRIP6) ELISA Kit (MODL01335)
$779
SEZ6 Antibody (PACO64941)
$407
TTC14 Antibody (PACO64997)
$407
OSTN Antibody (PACO64881)
$407
OR9G1 Antibody (PACO64877)
$407