The TRIP12 Polyclonal Antibody (CAB9958) is a valuable tool for researchers interested in studying TRIP12, a protein involved in various cellular processes such as protein degradation and DNA repair. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting experiments. By specifically binding to TRIP12, researchers can effectively detect and analyze the protein in a wide range of cell types, making it ideal for investigations in areas such as molecular biology and cancer research.TRIP12, also known as thyroid hormone receptor interactor 12, plays a crucial role in maintaining cellular homeostasis by regulating the turnover of proteins and repairing damaged DNA.
Its involvement in these fundamental processes highlights its importance in cell biology and disease development. By gaining a deeper understanding of TRIP12 and its functions, researchers may uncover potential therapeutic targets for conditions such as cancer, neurodegenerative diseases, and genetic disorders.Overall, the TRIP12 Polyclonal Antibody (CAB9958) offers a reliable tool for researchers seeking to explore the role of TRIP12 in cellular processes and disease pathways. Its specificity and sensitivity make it a valuable asset for furthering scientific understanding in various fields of study.
Product Name:
TRIP12 Rabbit Polyclonal Antibody
SKU:
CAB9958
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRIP12 (NP_001271143.1).
The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.
Purification Method:
Affinity purification
Gene ID:
9320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRIP12 Rabbit pAb (CAB9958) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
