TRIOBP Rabbit Polyclonal Antibody (CAB4485)
- SKU:
- CAB4485
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TRIOBP
- DFNB28
- HRIHFB2122
- TAP68
- TARA
- dJ37E16.4
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | TRIOBP Rabbit Polyclonal Antibody |
SKU: | CAB4485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-310 of human TRIOBP (NP_008963.3). |
Sequence: | DVTK LSDS NKEN ALHS YSTQ KGPL KAGE QRAG SEVI SRGG PRKA DGQR QALD YVEL SPLT QASP QRAR TPAR TPDR LAKQ EELE RDLA QRSE ERRK WFEA TDSR TPEV PAGE GPRR GLGA PLTE DQQN RLS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | TARA; TAP68; DFNB28; dJ37E16.4; HRIHFB2122; TRIOBP |
Positive Sample: | BxPC-3,U-87MG,HeLa,LO2,A-549,SW620,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Midbody, Nucleus, centrosome, cytoskeleton, cytoskeleton, microtubule organizing center. |
Calculated MW: | 261kDa |
Observed MW: | 70kDa |
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Purification Method: | Affinity purification |
Gene ID: | 11078 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |