The TRIM72 Polyclonal Antibody (CAB16751) is a crucial tool for researchers studying TRIM72, a protein involved in skeletal muscle development and regeneration. This rabbit-derived antibody has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TRIM72 protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for investigations in muscle biology and regenerative medicine.
TRIM72, also known as MG53, plays a key role in maintaining muscle membrane integrity and facilitating muscle repair after injury. Its importance in muscle physiology and regeneration has sparked interest in its potential therapeutic applications for muscle-related diseases and injuries. By studying TRIM72, researchers aim to uncover new insights into muscle health and function, leading to the development of innovative treatments for muscle disorders.
Product Name:
TRIM72 Polyclonal Antibody
SKU:
CAB16751
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of mouse TRIM72 (NP_001073401.1).
Enables identical protein binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; plasma membrane repair; and protein homooligomerization. Predicted to act upstream of or within negative regulation of insulin receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma.
Purification Method:
Affinity purification
Gene ID:
434246
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from C2C12 cells, using TRIM72 Rabbit pAb (CAB16751) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
