The TRIM62 Polyclonal Antibody (CAB15855) is a specialized tool for researchers investigating TRIM62, a key protein involved in the regulation of immune responses and antiviral defense mechanisms. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By specifically binding to the TRIM62 protein, this antibody enables precise detection and analysis in various cell types, making it an invaluable asset for studies in immunology, virology, and infectious disease research.TRIM62, a member of the tripartite motif (TRIM) protein family, plays a crucial role in modulating immune signaling pathways and promoting the antiviral response.
Its intricate functions in immune system regulation highlight its potential as a therapeutic target for diseases such as viral infections, autoimmune disorders, and inflammatory conditions. By elucidating the molecular mechanisms underlying TRIM62 activity, researchers can gain valuable insights that may lead to the development of novel treatment approaches aimed at enhancing immune defense mechanisms or curbing excessive immune responses.
Product Name:
TRIM62 Rabbit Polyclonal Antibody
SKU:
CAB15855
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_060677.2).
Sequence:
HEQH QVTG IDDA FDEL QREL KDQL QALQ DSER EHTE ALQL LKRQ LAET KSST KSLR TTIG EAFE RLHR LLRE RQKA MLEE LEAD TART LTDI EQKV QRYS QQLR KVQE GAQI LQER LAET DRHT FLAG VASL SERL KGKI HETN LTYE DFPT SKYT GPLQ Y
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:
DEAR1; TRIM62
Positive Sample:
A-431,Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
54kDa
Observed MW:
54kDa
Enables identical protein binding activity; transcription coactivator activity; and ubiquitin-protein transferase activity. Involved in several processes, including negative regulation of viral transcription; positive regulation of NF-kappaB transcription factor activity; and positive regulation of antifungal innate immune response. Is active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
55223
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRIM62 Rabbit pAb (CAB15855) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
