TRIM5 Rabbit Polyclonal Antibody (CAB17234)
- SKU:
- CAB17234
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TRIM5 Rabbit Polyclonal Antibody |
SKU: | CAB17234 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TRIM5 (NP_149083.2). |
Sequence: | EKLL LFCQ EDGK VICW LCER SQEH RGHH TFLT EEVA REYQ VKLQ AALE MLRQ KQQE AEEL EADI REEK ASWK TQIQ YDKT NVLA DFEQ LRDI LDWE ESNE L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RNF88; TRIM5alpha; TRIM5 |
Positive Sample: | HeLa,SGC-7901,Mouse stomach |
Cellular Localization: | Cytoplasm, Nucleus, P-body. |
Calculated MW: | 56kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 85363 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |