The TRIM49 Polyclonal Antibody (PAC017256) is a valuable tool for researchers studying TRIM49, a member of the tripartite motif (TRIM) protein family known for its involvement in various cellular processes, including immune response regulation and antiviral defense. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the TRIM49 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component in immunology and cancer research studies.
TRIM49 has been implicated in modulating immune responses and regulating inflammatory pathways, making it a promising target for therapeutic interventions in conditions such as cancer, autoimmune diseases, and viral infections. Understanding the functional role of TRIM49 is crucial for designing targeted therapies that manipulate immune responses effectively. With its specific reactivity and reliability, the TRIM49 Polyclonal Antibody is a key asset for researchers investigating the intricate mechanisms of immune regulation and disease pathogenesis.
Antibody Name:
TRIM49 Antibody (PACO17256)
Antibody SKU:
PACO17256
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Fusion protein of human TRIM49
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17256(TRIM49 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11.
Synonyms:
tripartite motif containing 49
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11. [provided by RefSeq, Aug 2010]
