TRIM34 Antibody (PACO20355)
- SKU:
- PACO20355
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TRIM34 Antibody (PACO20355)
The TRIM34 Polyclonal Antibody (PACO20355) is a valuable tool for researchers studying TRIM34, a protein involved in various cellular processes, including immune regulation and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TRIM34 protein, this antibody allows for accurate detection and analysis in a wide range of cell types, making it an ideal choice for studies in immunology and cancer research.TRIM34 is known for its role in immune response modulation and its contribution to the regulation of inflammatory pathways.
By targeting TRIM34, researchers can gain insights into its involvement in conditions such as cancer, autoimmune diseases, and chronic inflammation. Understanding the function of TRIM34 is crucial for the development of novel therapies that regulate immune responses and combat the progression of these diseases. The TRIM34 Polyclonal Antibody is a valuable tool for researchers looking to elucidate the role of TRIM34 in health and disease.
| Antibody Name: | TRIM34 Antibody (PACO20355) |
| Antibody SKU: | PACO20355 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human TRIM34 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20355(TRIM34 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20355(TRIM34 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. |
| Synonyms: | tripartite motif containing 34 |
| UniProt Protein Function: | TRIM34: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]Protein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 11p15Cellular Component: cytoplasm; cytosolBiological Process: positive regulation of transcription factor activity |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010] |
| UniProt Code: | Q9BYJ4 |
| NCBI GenInfo Identifier: | 55976584 |
| NCBI Gene ID: | 53840 |
| NCBI Accession: | Q9BYJ4.2 |
| UniProt Secondary Accession: | Q9BYJ4,Q9C016, Q9HCR0, Q9HCR1, Q9HCR2, D3DQS7 |
| UniProt Related Accession: | Q9BYJ4 |
| Molecular Weight: | 31,338 Da |
| NCBI Full Name: | Tripartite motif-containing protein 34 |
| NCBI Synonym Full Names: | tripartite motif containing 34 |
| NCBI Official Symbol: | TRIM34Â Â |
| NCBI Official Synonym Symbols: | IFP1; RNF21Â Â |
| NCBI Protein Information: | tripartite motif-containing protein 34 |
| UniProt Protein Name: | Tripartite motif-containing protein 34 |
| UniProt Synonym Protein Names: | Interferon-responsive finger protein 1; RING finger protein 21 |
| Protein Family: | Tripartite motif-containing protein |
| UniProt Gene Name: | TRIM34Â Â |
| UniProt Entry Name: | TRI34_HUMAN |
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