The TRIM27 Polyclonal Antibody (CAB6405) is a valuable tool for researchers studying TRIM27, a protein involved in cellular processes such as immune response and inflammation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the TRIM27 protein, this antibody allows for the detection and analysis of TRIM27 expression in various cell types, making it an essential tool for immuno-oncology and immunology research.TRIM27, also known as tripartite motif-containing 27, plays a crucial role in regulating immune responses and inflammatory pathways.
Its functions make it a promising target for studying diseases like cancer, autoimmune disorders, and inflammatory conditions. Understanding the role of TRIM27 in these processes is essential for developing novel therapies that target immune dysregulation and inflammatory diseases. The TRIM27 Polyclonal Antibody provides researchers with a powerful tool to advance their studies in these areas.
Product Name:
TRIM27 Rabbit Polyclonal Antibody
SKU:
CAB6405
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 214-513 of human TRIM27 (NP_006501.1).
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
Purification Method:
Affinity purification
Gene ID:
5987
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRIM27 antibody (CAB6405) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
