The TRIM26 Polyclonal Antibody (CAB15332) is a vital tool for researchers studying TRIM26, a member of the tripartite motif-containing protein family involved in various cellular processes, including antiviral defense and immune regulation. This antibody, produced in rabbits, is highly specific to human TRIM26 and is validated for use in Western blot applications. By targeting the TRIM26 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.
TRIM26 plays a crucial role in innate immunity by regulating the expression of antiviral genes and modulating immune signaling pathways. Its involvement in cell proliferation and apoptosis also makes it a potential target for therapeutic interventions in diseases such as viral infections and cancer. Understanding the functions of TRIM26 is essential for developing novel treatments that leverage its regulatory mechanisms to enhance immune responses or inhibit aberrant cell growth.
Product Name:
TRIM26 Rabbit Polyclonal Antibody
SKU:
CAB15332
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRIM26 (NP_001229712.1).
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRIM26 Rabbit pAb (CAB15332) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
