The Trim24 Polyclonal Antibody (CAB10546) is a valuable tool for researchers studying Trim24, a protein known for its role in regulating gene expression and cell proliferation. This antibody, produced in rabbits, is specifically designed to target Trim24 in human samples, making it an ideal choice for Western blot applications.Trim24, also known as TIF-1α, is a transcriptional co-regulator that plays a key role in various cellular processes, including development, metabolism, and immune response. Dysregulation of Trim24 has been linked to cancer, making it a potential therapeutic target for cancer treatment.
By using the Trim24 Polyclonal Antibody, researchers can effectively detect and analyze Trim24 in different cell types, providing valuable insights into its function and potential implications in disease development. This antibody is a valuable tool for studies in cancer biology, gene regulation, and molecular biology, helping advance our understanding of Trim24 and its impact on cellular processes.
Product Name:
TRIM24 Rabbit Polyclonal Antibody
SKU:
CAB10546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human TRIM24 (NP_056989.2).
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
8805
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRIM24 Rabbit pAb (CAB10546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
