TRIM23 Rabbit Polyclonal Antibody (CAB8329)
- SKU:
- CAB8329
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | TRIM23 Rabbit Polyclonal Antibody |
SKU: | CAB8329 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM23 (NP_001647.1). |
Sequence: | MATL VVNK LGAG VDSG RQGS RGTA VVKV LECG VCED VFSL QGDK VPRL LLCG HTVC HDCL TRLP LHGR AIRC PFDR QVTD LGDS GVWG LKKN FALL ELLE RLQN GPIG QYGA AEES IGIS GESI IRCD EDEA HLAS VYCT VCAT HLCS ECSQ VTHS TKTL AKHR RVPL ADKP HEKT MCSQ HQVH AIEF VCLE EGCQ TSPL MCCV CKEY GKHQ GHKH SVLE PEAN QIRA SILD MAHC IRTF TEEI SDYS RKLV GIVQ HIEG GEQI VEDG IGMA HTEH VPGT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ARD1; ARFD1; RNF46; TRIM23 |
Positive Sample: | PC-12,Mouse spleen,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Endomembrane system, Golgi apparatus membrane, Lysosome membrane. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Purification Method: | Affinity purification |
Gene ID: | 373 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |