TRIM2 Rabbit Polyclonal Antibody (CAB14393)
- SKU:
- CAB14393
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | TRIM2 Rabbit Polyclonal Antibody |
SKU: | CAB14393 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2). |
Sequence: | GVAA LQNN FFIT NLMD VLQR TPGS NAEE SSIL ETVT AVAA GKPL SCPN HDGN VMEF YCQS CETA MCRE CTEG EHAE HPTV PLKD VVEQ HKAS LQVQ LDAV NKRL PEID SALQ FISE IIHQ LTNQ KASI VDDI HSTF DELQ KTLN VRKS VLLM ELEV NYGL KHKV LQSQ LDTL LQGQ ESIK SCSN FTAQ ALNH GTET EVLL V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CMT2R; RNF86; TRIM2 |
Positive Sample: | Mouse small intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 82kDa |
Observed MW: | 81kDa |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23321 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |