Anti-TRIM14 Antibody (PACO17254)

Antibody Name:	TRIM14 Antibody (PACO17254)
Antibody SKU:	PACO17254
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Fusion protein of human TRIM14

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17254(TRIM14 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute.
	The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17254(TRIM14 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).

Background:	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants.
Synonyms:	tripartite motif containing 14

UniProt Protein Function:	TRIM14: Inhibits the transcriptional activity of SPI1 in a dose- dependent manner. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulationChromosomal Location of Human Ortholog: 9q22.33Cellular Component: cytoplasm; intracellularMolecular Function: zinc ion bindingBiological Process: negative regulation of viral transcription; innate immune response; positive regulation of transcription factor activity; activation of NF-kappaB transcription factor
UniProt Protein Details:
NCBI Summary:	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
UniProt Code:	Q14142
NCBI GenInfo Identifier:	15208663
NCBI Gene ID:	9830
NCBI Accession:	NP_055603.2
UniProt Secondary Accession:	Q14142,Q548W9, Q5TBQ8, Q6ZWL7, Q9BRD8, Q9C020, A8K9W0 E7EQC4, F8W956
UniProt Related Accession:	Q14142
Molecular Weight:
NCBI Full Name:	tripartite motif-containing protein 14
NCBI Synonym Full Names:	tripartite motif containing 14
NCBI Official Symbol:	TRIM14
NCBI Official Synonym Symbols:
NCBI Protein Information:	tripartite motif-containing protein 14
UniProt Protein Name:	Tripartite motif-containing protein 14
UniProt Synonym Protein Names:
Protein Family:	Tripartite motif-containing protein
UniProt Gene Name:	TRIM14
UniProt Entry Name:	TRI14_HUMAN

Antibodies

TRIM14 Antibody (PACO12903)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)