The TRHR Polyclonal Antibody (CAB15235) is a valuable tool for researchers studying the thyrotropin-releasing hormone receptor (TRHR), a key protein involved in the regulation of thyroid function. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in applications such as Western blotting.TRHR plays a crucial role in the hypothalamic-pituitary-thyroid axis, which controls the release of thyroid hormones essential for metabolism, growth, and development. Dysregulation of TRHR signaling has been linked to thyroid disorders and metabolic conditions, making it a promising target for therapeutic interventions.
By specifically binding to TRHR, this polyclonal antibody enables precise detection and analysis of this important receptor in various cell types. Its applicability in research areas such as endocrinology, neurobiology, and drug development makes it an indispensable tool for investigating the mechanisms underlying thyroid function and related disorders.Unlock the potential of your research with the TRHR Polyclonal Antibody (CAB15235) from Assay Genie.
Product Name:
TRHR Rabbit Polyclonal Antibody
SKU:
CAB15235
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-398 of human TRHR (NP_003292.1).
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance.
Purification Method:
Affinity purification
Gene ID:
7201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using TRHR Rabbit pAb (CAB15235) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
