The TRHDE Polyclonal Antibody (CAB10300) is a valuable tool for researchers studying TRHDE, a key enzyme involved in thyroid hormone regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TRHDE protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it ideal for investigations in endocrinology and metabolism.TRHDE plays a crucial role in the conversion of thyroxine (T4) to the active thyroid hormone triiodothyronine (T3), making it essential for proper thyroid function.
Dysregulation of TRHDE has been implicated in thyroid disorders such as hypothyroidism and hyperthyroidism, as well as metabolic conditions like obesity and diabetes. Understanding the role of TRHDE is essential for unraveling the complex mechanisms of thyroid hormone metabolism and developing targeted therapies for related diseases.Overall, the TRHDE Polyclonal Antibody (CAB10300) is a versatile tool that can advance research in endocrinology, metabolism, and thyroid disorders, providing valuable insights into the intricate pathways that govern hormone regulation and metabolic homeostasis.
Product Name:
TRHDE Rabbit Polyclonal Antibody
SKU:
CAB10300
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 62-200 of human TRHDE (NP_037513.1).
This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.
Purification Method:
Affinity purification
Gene ID:
29953
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of 22Rv1 cells, using TRHDE antibody (CAB10300) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
