The TRH Polyclonal Antibody (CAB8322) offered by Assay Genie is a valuable tool for research involving TRH, a neuropeptide involved in the regulation of thyroid function and metabolism. This antibody, produced in rabbits, is highly specific for TRH and has been validated for use in various applications including immunohistochemistry, ELISA, and Western blotting.TRH, also known as thyrotropin-releasing hormone, plays a crucial role in the hypothalamic-pituitary-thyroid axis, regulating the release of thyroid-stimulating hormone (TSH) and ultimately affecting thyroid hormone production.
Dysregulation of TRH signaling has been implicated in thyroid disorders, metabolic diseases, and neurological conditions.By utilizing the TRH Polyclonal Antibody, researchers can accurately detect and analyze TRH expression in various tissues and cell types, allowing for a better understanding of its physiological functions and potential therapeutic applications. This antibody is a valuable tool for studies in endocrinology, neurology, and metabolism research.
Product Name:
TRH Rabbit Polyclonal Antibody
SKU:
CAB8322
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 25-230 of human TRH (NP_009048.1).
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
Purification Method:
Affinity purification
Gene ID:
7200
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRH Rabbit pAb (CAB8322) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
