TREX1 Rabbit Polyclonal Antibody (CAB6778)
- SKU:
- CAB6778
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TREX1 Rabbit Polyclonal Antibody |
SKU: | CAB6778 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TREX1 (NP_057465.1). |
Sequence: | MGPG ARRQ GRIV QGRP EMCF CPPP TPLP PLRI LTLG THTP TPCS SPGS AAGT YPTM GSQA LPPG PMQT LIFF DMEA TGLP FSQP KVTE LCLL AVHR CALE SPPT SQGP PPTV PPPP RVVD KLSL CVAP GKAC SPAA SEIT GLST AVLA AHGR QCFD DNLA NLLL AFLR RQPQ PWCL VAHN GDRY DFPL LQAE LAML GLTS ALDG AFCV DSIT ALKA LERA SSPS EHGP RKSY SLGS IYTR LYGQ SPPD SHTA EGDV LALL SICQ WRPQ AL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CRV; AGS1; DRN3; HERNS; RVCLS; TREX1 |
Positive Sample: | HeLa,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, cytosol. |
Calculated MW: | 33kDa |
Observed MW: | 35kDa |
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 11277 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |