The TRERF1 Polyclonal Antibody (PAC020759) is a powerful tool for researchers studying TRERF1, a transcriptional regulator involved in cell proliferation and differentiation. This antibody, produced in rabbits, is specifically designed to recognize TRERF1 in human samples and is validated for Western blot applications. By binding to the TRERF1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in molecular biology and cancer research.TRERF1, also known as transcriptional regulatory factor, plays a crucial role in controlling gene expression and cellular functions. Its involvement in cell growth and differentiation makes it a key player in various biological processes, including development and disease progression.
Understanding the mechanisms by which TRERF1 operates is essential for uncovering its potential role in pathologies such as cancer, neurodegenerative disorders, and developmental abnormalities.With its high specificity and sensitivity, the TRERF1 Polyclonal Antibody (PAC020759) offers researchers a reliable tool for investigating the functions and regulatory pathways associated with TRERF1. Its versatility and efficacy make it a valuable asset for advancing scientific knowledge and potentially unlocking new therapeutic targets for various diseases.
Antibody Name:
TRERF1 Antibody (PACO20759)
Antibody SKU:
PACO20759
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human TRERF1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20759(TRERF1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms:
transcriptional regulating factor 1
UniProt Protein Function:
Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
UniProt Protein Details:
NCBI Summary:
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
