The Trerf1 Polyclonal Antibody (PAC012899) is a valuable tool for researchers studying Trerf1, a key transcriptional regulator involved in various cellular processes. This antibody, produced in rabbits, has high reactivity towards human samples and is validated for use in Western blot applications. By binding to the Trerf1 protein, this antibody allows for the detection and analysis of Trerf1 in different cell types, making it ideal for studies in molecular biology and gene expression research.Trerf1, also known as transcriptional enhancer factor 1-related factor 1, plays a crucial role in the regulation of gene expression by binding to specific DNA sequences and modulating transcription.
Its involvement in various cellular pathways makes it a promising target for investigation in fields such as development, differentiation, and disease mechanisms. Understanding the function of Trerf1 can provide valuable insights into the underlying molecular mechanisms of various biological processes and diseases, paving the way for novel therapeutic strategies.
Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
UniProt Protein Details:
NCBI Summary:
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
