The TREML1 Polyclonal Antibody (CAB10414) is a powerful tool for researchers studying TREML1, a cell surface protein with emerging roles in regulating immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in various applications, including Western blot analysis. By specifically binding to the TREML1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in immunology and cancer research.TREML1, also known as triggering receptor expressed on myeloid cells-like 1, is a key player in immune regulation, influencing processes such as inflammation and immune cell activation.
Its involvement in modulating immune responses makes it a promising target for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the functions of TREML1 is crucial for developing targeted therapies that manipulate immune responses in the context of these diseases. Overall, the TREML1 Polyclonal Antibody (CAB10414) is a valuable asset for researchers looking to uncover the intricate roles of TREML1 in immune regulation and its implications for various disease processes.
Product Name:
TREML1 Rabbit Polyclonal Antibody
SKU:
CAB10414
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1).
Cell membrane, Cytoplasm, Single-pass type I membrane protein.
Calculated MW:
33kDa
Observed MW:
33kDa
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants
Purification Method:
Affinity purification
Gene ID:
340205
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TREML1 antibody (CAB10414) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
